If you have HPV but eventually clear it from your body, can you get reinfected with it?

by Rachel on March 21, 2011

Doing a project on HPV but can’t seem to find the answer to this question. Once HPV has been ridden from your system, can it come back?

{ 6 comments… read them below or add one }

Himynameis March 21, 2011 at 11:34 pm

Well,people and doctors will not officially say it’s and STD,it can be. That is one source. Once you have taken care of it,no you cannot get the same strain back,but you can get a different form or stronger strain if in contact with it again.

HnD718 March 21, 2011 at 11:36 pm

HPV is a virus and never leaves your system. You can break out a couple of times but even if you dont break or dont have any symptoms its STILL in your blood stream… and can pass it on.

Karla March 22, 2011 at 12:21 am

hpv remains in your body forever its a virus. sadly there is no cure yet for it.

aisydaisylady March 22, 2011 at 12:37 am

There is no cure for HPV.

it can be repressed by the body to a tolerable level. But there is no ridding it from the body.

Once infected, it remains in the body and can be activated when the body is stressed. (insomnia, anorexia, low nutrition etc.

This you can do:
Eat healty diet, include a multivitamin ( I reccomend Pre-Natal vitamins if you are of reproductive age. Doesnt matter if you are not pregnant. They are just better. Get plenty of sleep. The bodys immunity when boosted can help keep symptoms from appearing.

Hope this helps! :)

Ruth March 22, 2011 at 12:55 am

HPV is a viral infection. As with most viral infections, they lie dormant in your body. The symptoms may go away but, the virus is still in your body. Viruses’ are prone to have flare-ups and remissions. The symptoms go away then come back. Unless, you have been treated for HPV ( either by Colposcopy or LEEP Procedure ), even after such procedures, you need to have repeated Pap Smears for ” x ” amount of times, before you are considered ” cured”. But, even then, it may return. Fortunately, there is now a vaccine to help prevent from being infected by HPV. If you have tested positive for HPV, please follow your Doc’s instructions and have check-ups when recommended. HPV can lead to Cervical Cancer, so, it is necessary to follow your Doc’s suggestions. Almost 80% of young females are HPV positive so, you are not alone. Just be aware of what you need to do and you’ll be OK. I hope that this helps.

tarnishedsilverheart March 22, 2011 at 12:56 am

The virus is never rid from the body the virus lays in a state where is usually does not cause any problems.

Once you acquire an HPV type you can’t get that HPV type again however your HPV type can reactivate and you can acquire new HPV types with new sex partners.

Here is the article that was published several years ago showing the replication of the virus. It will be a good source for your paper. You may also want to look at the info on these famous HPV researchers

UAB Researchers Make Breakthrough Discovery of HPV Replication

Posted on March 15, 2004 at 4:00 p.m.

BIRMINGHAM, AL — Researchers at UAB (University of Alabama at Birmingham) have discovered the mechanism used by a common virus to replicate itself and remain in the human body for decades. Human papillomavirus (HPV), a family of over 100-related viruses, are responsible for a variety of medical conditions, ranging from benign hand or foot warts to genital warts, cervical cancer and recurrent respiratory papillomatosis, a potentially fatal disease in children.

In an article published in the Proceedings of the National Academy of Sciences in March, the research team reports that a viral replication protein known as E2 binds the circular viral DNA to cell structures called spindle fibers that are present in a cell when it divides, a process known as mitosis. In mitosis, a single cell divides in two, creating two genetically identical daughter cells. By latching onto the spindle fibers of the cell as it divides, HPV DNA also divides and replicates itself in each of the new daughter cells where it can continue to replicate and persist indefinitely.

“In effect, HPV is able to mimic our own chromosomes, behaving as a sort of ‘mini-chromosome’, independently replicating and keeping pace as the cellular chromosomes replicate and the cell divides,” says Tom Broker, Ph.D., professor of biochemistry and molecular genetics and co-author of the paper. “This allows the virus to remain in our bodies indefinitely, with the potential of causing serious disease years, even decades, after first exposure.”

Broker says that virtually all humans carry at least one type of HPV for much of their lives, usually transmitted to the external skin very early in life or to the internal mucosal lining later during sexual contact. For most people, the virus persists at low levels without causing obvious disease, and the body’s immune system keeps it in check.

However, in some people, the virus can become activated and cause lesions, particularly if the infected tissue is repeatedly injured, or following periods of emotional or physical stress, during pregnancy, as a result of immunosuppressive therapy for immune disorders or organ transplantation, as a outcome of progressing HIV/AIDS, and even as a consequence of aging.

“This is a major breakthrough in our quest to find ways to treat the myriad conditions associated with HPV,” says Louise Chow, Ph.D., professor of biochemistry and molecular genetics and co-author of the paper. “This improves our understanding of the mechanisms the virus uses to reproduce. We now have new molecular targets to aim at for antiviral drug discovery.”

HPV’s special mechanism for attaching itself to the mitotic spindles and getting pulled into the daughter cells has not been observed with other families of viruses, according to Chow.

There are about 15,000 new cases of cervical or penile cancer attributed to HPV each year in the US, and nearly 5000 deaths. Worldwide, 600,000 cases occur annually, especially in developing countries without advanced medical diagnostic methods such as Papanicolaou (Pap) smear screening, which can detect the activation of HPV early enough for aggressive treatment to be successful.

HPV infection in the throat and respiratory tract, laryngeal papillomatosis, can cause recurrent respiratory papillomatosis in children, who are usually infected at birth from contact with HPV-caused genital warts present in the mother. There are an estimated 2,000 cases per year in the United States

This research was funded by grants from the United States Public Health Service and the National Cancer Institute, one of the National Institutes of Health. Tom Broker is the President of the International Papillomavirus Society. More information on HPV and associated disease can be found at the society’s Web site at http://www.IPVSoc.org.

The first author of the publication is Brian A. Van Tine, for whom this project formed part of his Ph.D. thesis. Van Tine is currently completing his medical training at UAB, supported in part by the Medical Student Training Program for the M.D., Ph.D. combined degree.

The article can be read online at http://www.pnas.org/cgi/doi/10.1073/pnas.0306848101.

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