Pathophysiology For Genital Warts

by Rachel on July 30, 2010

papilloma viruses are highly species-specific and not infect other species, even in laboratory conditions. Man is the only known reservoir for HPV. papillomavirus virus are nonenveloped icosahedral symmetry of 72 capsomers a genome DNA double-stranded circular surround of about 8000 base pairs.

Papillomavirus may have two modes of replication. A stable episomal replication of the genome in basal cells, the other escaped or vegetative replication of differentiated cells to produce progeny virus. Although all cells contain a lesion of the viral genome, viral gene expression is closely associated with the state of cellular differentiation.

Most viral genes are activated only in infected leaves of the basal layer of keratinocytes. The production of viral particles can occur only in highly differentiated keratinocytes, thus the production of virus occurs only pushed to the surface, where epithelial cells are ultimately in the environment.

HPV lesions are considered from the proliferation of basal keratinocytes infected. The infection usually occurs in the basal cells of the host of infectious virus are disrupted by an epithelial barrier would be exposed, that during sex and after minor abrasions.

HPV infections have been shown to be not cytolytic, but viral particles as a result of degeneration of cells are released peeling. The HPV virus can survive for several months at low temperatures without a host, that is, a person with plantar warts, the virus can spread by walking barefoot.

virus replication is limited in the nucleus. Therefore, infected cells show a high degree of nuclear atypia. Koilocytosis (Greek Koilos if empty) describes a combination of perinuclear clearing (HALO) with a pyknotic nucleus or narrowed and is a feature of productive papillomavirus infection.

The HPV genome is a circular episomal DNA separate from the host cell nucleus in benign or low-risk HPV, as it is usually associated with HPV types 6 and 11. The genomes of types of high risk HPV 16 and 18 are usually integrated into the host cell DNA in malignant lesions.

The integration of the viral genome into the genome of the host cell as an indicator of malignant transformation. proteins E6 and E7 HPV serotype at high risk have shown that proteins of the host tumor suppressor p53 and Rb inactivation, so that the unregulated proliferation of the host cell and malignant transformation.

Genital warts can vary in appearance. You can be very small, can occur in clusters and can not in large masses in the genital area to develop. They seem so common among women than men. They occur either in the vagina, cervix, or around the anus in women. In men, they usually occur in the head or shaft of the penis and scrotum and the anus. Genital warts treatments must be able to both visual symptoms and eliminate the virus to be truly effective.

Most physicians use cautery or freezing as a first option to cure genital warts. Unfortunately, the success of this method is achieved often temporary, and the warts soon. For genital warts, treatment may include surgery under excise or burn them. be used after surgery or chemical acids, we can expect a scar in this area.

Surgical intervention as a remedy against HPV are trying to stimulate not only cut the virus, but also inflammation in the tissue. The theory is that the body will develop an immune response against the virus to prevent recurrence. However, this method cure for genital warts are often not removed when doctors are unable to virus in its entirety as it often becomes lodged in the deeper layers of skin to skin.

HPVCurative cure is a new very efficient and powerful for genital warts. It is noted cures for his role in the field of genital warts, and the total clearance of the infection and over again. It contains organic plant extracts and anti-viral essential oils, the ability, as a remedy against HPV have shown in laboratory certified to act. The results are guaranteed.

Users experience HPVCurative rapid withdrawal of genital warts without scarring or recurrence. The treatment is painless and gives excellent results when compared to other treatments against HPV. It eliminates genital warts and skin tissue goes to the state it was before the infection. As the treatment to effectively eliminate genital warts and wart-like substances on the genitals, the surgical treatment of acid or HPV may soon be a thing of the past.

HPVCurative has powerful medicinal properties that reduce the astonishing capacity, tumor growth of HPV. The organic extracts in this treatment and the features of stimulation and thus strengthen the immune system. For more information, visit http://www. bcured. net.

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